Beta-Nicotinamide Mononucleotide Chemicals Raw Powder Beta-NMN Anti-Aging Drugs

Beta-Nicotinamide Mononucleotide Chemicals Raw Powder Beta-NMN Anti-Aging Drugs

Beta-Nicotinamide Mononucleotide Chemicals Raw Powder Beta-NMN Anti-Aging Drugs Basic Info Description: Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also...

Product Details

Beta-Nicotinamide Mononucleotide Chemicals  Raw Powder Beta-NMN Anti-Aging Drugs  

Basic Info


Product NameBeta-Nicotinamide Mononucleotide
Aliasbeta-NMN
CAS1094-61-7
MFC11H15N2O8P
MW334.22
EINECS214-136-5
Purity99.50%
GradePharmaceutical Grade
AppearanceWhite Powder
StandardUSP
StockMass Stock
Packing Methodsdesigned disguised packing ways, 100% pass custom guarantee
Delivery timewithin 24 hours after payment confirmed
PaymentT/T, Western Union,Money Gram , Bitcoin
UsageTrilostane is an inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.


Description:


Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Beta-Nicotinamide Mononucleotide Application:


The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways.

NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.

NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth.

However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.



Storage

1)Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

2)Keep out of the reach of children.

3)Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.


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