|Product Name||Beta-Nicotinamide Mononucleotide|
|Packing Methods||designed disguised packing ways, 100% pass custom guarantee|
|Delivery time||within 24 hours after payment confirmed|
|Payment||T/T, Western Union,Money Gram , Bitcoin|
|Usage||Trilostane is an inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.|
Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
Beta-Nicotinamide Mononucleotide Application:
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways.
NMNAT (EC 22.214.171.124) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.
NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability. In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth.
However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.
1)Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
2)Keep out of the reach of children.
3)Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Our Order Process:
|Step 1||Please tell me in what products you are interested, quantities, and the destination country.|
|Step 2||You confirm all details and offer us purchase order.|
|Step 3||We offer the quotation of products and suitable shipping method for reference.|
|Step 4||You confirm the order and pay money 100% in advance and send us your contact information including contacting person,address,mobile number etc.|
|Step 5||We arrange the shipment according to your requirements and tracking number will be offered after confirming the payment within 24h|
|Step 6||We offer after-sales service after you receive products.|
What about the payment? Is it secure?
A: Payment can be TT, West Union, Money Gram. As a well-known supplier, thousands of buyers pay as mentioned. It is warmly welcome to visit our company, discuss and deal face to face.
Do you accept sample order?
A:Yes,we accept small order from 10g,100g and 1kg for your evaluation quality of our goods.
Is there any discount?
A:Yes,for larger quantity,we always support with better price.
Do you have any reshipment policy?
Yes we will reship for totally free if your parcles is seizd by customs unlucky,you dont need to pay any more money.