Baclofen Alcoholism Treatment

Baclofen Alcoholism Treatment

Antispasmodic Agent Powder Baclofen For Treat Muscle Symptom , CAS 1134-47-0

Product Details

Baclofen quick detail:

Product Name: Baclofen
Tag: gamma-aminobutyric acid, GABA, Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan

Synonym Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan

CAS 1134-47-0

MF C10H12ClNO2

MW 213.66

EINECS 214-486-9

Assay 99%

Quality Standards Enterprise Standard/Pharma Grade

Appearance White powder

Package 25kg/Drum

Place of Origin China

Certification ISO9001, ISO14000, KOSHER

Model Number 1134-47-0

MOQ 1 kg

Packaging Details 25kg/Drum, 1kg/bag

Delivery Time 1-2 days

Payment Terms T/T, Western union, Money gram

Supply Ability 500000 T/Month

Baclofen description:

(1) Baclofen (brand names Kemstro, Lioresal, Liofen, Gablofen, Lyflex, Beklo and Baclosan) is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

(2) It is an agonist for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.

(3)A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment. 3. Medical uses: Baclofen is primarily used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, cerebral palsy, and multiple sclerosis. Its use in people with stroke or Parkinson's disease is not recommende. 4. Mechanism of action: Baclofen produces its effects by activating the GABAB receptor, similar to the drug which also activates this receptor and shares some of its effects. However, baclofen does not have significant affinity for the receptor, and has no known abuse potential. The modulation of the GABAB receptor is what produces baclofen's range of therapeutic properties.


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