Pharmaceutical Raw Materials Quetiapine Fumarate

Pharmaceutical Raw Materials Quetiapine Fumarate

Pharmaceutical Raw Materials Quetiapine Fumarate Quick details English name: QUETIAPINE HEMIFUMARATE CAS No .: 111974-72-2 Molecular formula: C46H54N6O8S2 Molecular weight: 883.09 Standard: Enterprise standard Natural / synthetic: synthetic Level: Medical grade Content: 99% Appearance: white...

Product Details

Pharmaceutical Raw Materials Quetiapine Fumarate 


Quick details 


English name: QUETIAPINE HEMIFUMARATE
CAS No .: 111974-72-2
Molecular formula: C46H54N6O8S2
Molecular weight: 883.09
Standard: Enterprise standard
Natural / synthetic: synthetic
Level: Medical grade
Content: 99%
Appearance: white powder
Category: Pharmaceutical raw materials
Industry: Medicine
Area: Non-antipsychotic drugs


Use:

Quetiapine fumarate is an antipsychotics, developed by the United States AstraZeneca, a variety of neurotransmitter receptors interact in the brain, the serotonin (5-HT2) receptor Has a high affinity and is greater than the affinity for dopamine D1 and dopamine D2 receptors in the brain. Quetiapine also has high affinity for the histamine H1 receptor and the adrenergic alpha 1 receptor with low affinity for the adrenergic alpha 2 receptor but not for the cholinergic muscarinic receptor or the benzodiazepine receptor No affinity. Counteracting psychotic activity measurements such as conditioned avoidance reflex positive results. Clinically, it is mainly used for the treatment of major depressive disorder in adults, acute manic episode of bipolar disorder and various types of schizophrenia. Not only positive symptoms of schizophrenia effective, negative symptoms have some effect. It also alleviates the emotional symptoms associated with schizophrenia such as depression, anxiety and cognitive deficits. Mainly used to treat schizophrenia.


COA 

Product nameQuetiapine fumarate
CAS:111974-72-2Outer packaging25kg/Drum
Production date
shelf life2 years
Items of analysisSpecificationresults
DescriptionWhite crystalline powder;odorless(Visual)pass
solubilityfreely soluble in glacial acetic acid,slightly soluble in water and ethanol.pass
identification1.positive reaction of potassium permanganate.
2.consistent with the IR spectrum of the standard
pass
pass
acidity(pH)5.0-6.05.4
melting point171.0-176.0ºC174.2-174.8ºC
Heavy metals≤20ppm<20ppm
water %≤0.5%0.12%
chloride≤0.02%<0.020%
sulphated ash≤0.1%0.06%
DTO impurity≤0.15%ND
CDT impurity≤0.15%ND
EPD impurity≤0.15%0.04%
Any unknown impurity≤0.10%0.07%
Total impurities≤0.5%0.12%
assayQuetiapine Fumarate 99.0%~101.0%(anhydrous substance)100.1%
methanol≤2000ppmND
ethanol≤2000ppm771ppm
acetone≤2000ppmND
n-hexane≤290ppmND
toluene≤890ppmND
total bacterial count≤1000cfu/g (in-house)<10cfu/g
total yeasts & moulds count≤100cfu/g (in-house)<10cfu/g
escherichia coliabsent (in-house)ND
conclusionqualified


Our Advantage:


Quality guaranteed: all our products are in 99% or more purity


Packing ways: effective discreet packing ways for different product, different amount and different areas


Delivery and reship policy: we support China EMS, HongKong Post ect.,99% pass through customs, but at unexpected situations, we also support reship


Delivery time: 5-12 working days

Payment term: western union, money gram,bank transfer

 


How to make the payment?


1 Let me know the item, quantity and the destination country


2 After you confirm all details of order, pay money and give us Shipping address.


3 We can accept Western Union, Money Gram and Paypal as well.


4 We arrange the shipment at first time after receive payment and give you the tracking number


5 We will supply after-sales service after you receive parcel.


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