Prostate Cancer Treatment Powder Gnrh Triptoreli 2mg/Vial

Prostate Cancer Treatment Powder Gnrh Triptoreli 2mg/Vial

Triptorelin is a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) and a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts.

Product Details

Function of Triptorelin

Triptorelin is a gonadotropin releasing hormone (GnRH) agonist that is a potent inhibitor of the synthesis of estrogen (in women) and is used to treat advanced prostate cancer. It is D-tryptophan substitution at residue 6. It is a medication that causes stimulation of the pituitary, thus decreasing secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH).

COA:

Triptorelin GNRH Specifications
AppearanceWhite powder
Appearance of solutionTransparent
Colour of solutionColorless
pHoffer
Specific Optical Rotation (c=0.5,95%HAc)-65.0~-75.0
Purity(by HPLC)≥98.00%~99.90%
Total Impurities(by HPLC)≤2.00%~0.10%
Single Impurity(by HPLC)≤0.50%~0.03%
Water Content(Karl Fischer)≤4.80%
Acetate Content(by HPLC)≤6.80%
Peptide Content(by %N )≥88.00%
Amino Acaid Composition±10% of theoretical
Assay(By anhydrous, acetic acid-free)95.0%~105.0%
Solubilityoffer
storageNormal store:2-8ºC
Long-term storage:-20±5ºC
PaackageGlassVial or as required


Description


Triptorelin is a form of hormone therapy called an LHRH (luteinizing hormonereleasing hormone) agonist. There are two brands of the same drug, which are called Decapeptyl SR and Gonapeptyl Depot. Triptorelin slows down the growth of prostate cancer cells by blocking a message from the brain telling the testicles to produce . Most prostate cancer cells need to grow and spread.
Triptorelin, a decapeptide,is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is also used as therapy in cases of gender dysphoria.


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