Prostate Cancer Treatment Powder Gnrh Triptoreli 2mg/Vial
Triptorelin is a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) and a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts.
Function of Triptorelin
Triptorelin is a gonadotropin releasing hormone (GnRH) agonist that is a potent inhibitor of the synthesis of estrogen (in women) and is used to treat advanced prostate cancer. It is D-tryptophan substitution at residue 6. It is a medication that causes stimulation of the pituitary, thus decreasing secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH).
Triptorelin GNRH Specifications
Appearance of solution
Colour of solution
Specific Optical Rotation (c=0.5,95%HAc)
Total Impurities(by HPLC)
Single Impurity(by HPLC)
Water Content(Karl Fischer)
Acetate Content(by HPLC)
Peptide Content(by %N )
Amino Acaid Composition
±10% of theoretical
Assay(By anhydrous, acetic acid-free)
Normal store:2-8ºC Long-term storage:-20±5ºC
GlassVial or as required
Triptorelin is a form of hormone therapy called an LHRH (luteinizing hormonereleasing hormone) agonist. There are two brands of the same drug, which are called Decapeptyl SR and Gonapeptyl Depot. Triptorelin slows down the growth of prostate cancer cells by blocking a message from the brain telling the testicles to produce . Most prostate cancer cells need to grow and spread. Triptorelin, a decapeptide,is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is also used as therapy in cases of gender dysphoria.
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