99% Purity Drugs Pain Killer Pharmaceutical Octenidine Dihydrochloride Octenidine HCl Cas 0775-75-6
Product name:Octenidine Dihydrochloride
Molecular Formula: C36H62N42HCl
Shelf life:2 years
Product description :Octenidine is absorbed neither through the skin nor through mucous membranes nor via wounds and does not pass the placental barrier.It is primarily used as an antiseptic.
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-1, Product Name: Octenidine HCl
-2, Specification & Standard: USP /EP /BP 99.5%
-3, CAS #: 70775-75-6
-4, Description: White, yellowish white crystalline powder
-5, Function of Octenidine HCl
Octenidine dihydrochloride is a topical antimicrobial used in personal care and medical industry. It is similar in its action to the quaternary ammonium compounds (quats), but is of somewhat broader spectrum of activity.
Octenidine is currently increasingly used in continental Europe as a substitute for quats or chlorhexidine (with respect to its slow action and concerns about the carcinogenic impurity 4-chloroaniline) in water- or alcohol-based skin, mucosa and wound antiseptics. In aqueous formulations, it is often potentiated with addition of 2-phenoxyethanol.
As topical antimicrobial agents, Octenidine is typically used for skin, mucous membrane and open wound decontamination. Octenidine meets the need for a broad-spectrum antimicrobial suitable for wound care.
First launched in the UK during 1990, octenidine is available in three formulations in the UK: octenilin wound gel (0.05% octenidine); octenilin wound irrigation solution (0.05% octenidine); and octenisan wash lotion (0.3% octenidine) for decolonisation.
Octenidine is more active than 4% chlorhexidine against S aureus, Staphylococcus epidermidis, Proteus mirabilis, Streptococcus pyogenes, Klebsiella pneumoniae, Escherichia coli and Candida albicans, etc.
At concentrations of <1.5M, octenidine reduced numbers of these bacteria by 99% within 15 minutes. However, the wound environment may modify bacteriological potency recorded in culture: 8% serum reduces the effectiveness of chlorhexidine between 2.5 and 35-fold. In vitro, the addition of pus or 25% blood reduces chlorhexidine's effectiveness by around 1-log step. In contrast, blood (up to 10%), albumin and mucin do not undermine octenidine's efficacy. This observation suggests that products containing octenidine retain antibacterial efficacy when applied to wounds.
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