99% Purity Pharmaceutical Raw Materials Cabozantinib CAS 849217-68-1 API Powder Cabozantinib Malate XL184 In Stock with High Quality and Good Price for Sale
99% Cabozantinib powder
Product name: Cabozantinib
Product Name: Supply cabozantinib/ XL184 CAS:849217-68-1
Testing Method: HPLC
Appearance: white fine powder
Cabozantinib (marketed under the tradename Cometriq, formerly known as XL184) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM. XL-184 also displays potent activity against Met, Ret, Kit, FLT1, FLT3, FLT4, Tie2, and AXL. XL184 at low concentration(0.1-0.5 μM) is sufficient to induce marked inhibition of constitutive and inducible Met phosphorylation and its resultant downstream signaling in MPNST cells, and inhibit HGF-induced MPNST cell migration and invasion.
White to off-white crystalline powder with a characteristic sulfide-like order
IR:similar to Reference Standard
Appearance of solution
Clear and colorless
Loss on Drying
2.0 to 2.6
1. 1. Single Impurity ≤1.0%
98.0% to 101.5%
Cabozantinib (sold under the trade name Cometriq, formerly known as XL184) is an effective VEGFR2 inhibitor with an IC50 of 0.035 nM. XL-184 also shows effective activity against Met, Ret, Kit, FLT1, FLT3, FLT4, Tie2 and AXL. Low concentrations (0.1-0.5 [mu] M) of XL184 were sufficient to induce significant inhibition of histological and inducible Met phosphorylation and its downstream signaling in MPNST cells and inhibit HGF-induced migration and invasion of MPNST cellsn
The quality control process
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
Four steps: sampling, sample pretreatment, measuring and data processing.
a) Each operator must do self-inspection of producs and make the corresponding inspection records.
b) Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
We have clients throughout the world.
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2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
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